KOtBu-mediated stereoselective addition of quinazolines to alkynes under mild conditions.
نویسندگان
چکیده
A facile alkenylation of quinazolines with unactivated terminal alkynes has been achieved in the presence of KOtBu without the aid of any transition metal catalysts. The reaction is carried out under very mild conditions and shows a high stereoselectivity. A possible radical-based mechanism is also explored.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 11 35 شماره
صفحات -
تاریخ انتشار 2013